1192649-65-2Relevant academic research and scientific papers
Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors
Zhuang, Weiping,Zhao, Xueqing,Zhao, Gang,Guo, Lihe,Lian, Yunyang,Zhou, Jingming,Fang, Dongsheng
experimental part, p. 6540 - 6546 (2009/12/24)
Preparation for the N-alkylated derivatives of enantiomerically pure (2S)-4-fluoroproline and (2S)-4-fluoropyrrolidine-2-acetic acid is described. The final compounds were evaluated as potential GAT-1 uptake inhibitors via cultured cell lines expressing m
