1192674-14-8

Basic information

• Product Name: (R)-[(2R,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl]-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-methanol
• Synonyms: (R)-[(2R,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl]-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-methanol
• CAS NO: 1192674-14-8
• Molecular Weight: 359.425
• Mol File: 1192674-14-8.mol

Chemical Properties

• CAS DataBase Reference: (R)-[(2R,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl]-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-[(2R,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl]-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-methanol(1192674-14-8)
• EPA Substance Registry System: (R)-[(2R,5R)-5-isopropyl-3,6-dimethoxy-2,5-dihydropyrazin-2-yl]-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-methanol(1192674-14-8)

Safety Data

• Hazardous Substances Data: 1192674-14-8(Hazardous Substances Data)

Upstream product

• 1192674-09-1 (5R)-5-phenyl-4,5-dihydroisoxazole-3-carbaldehyde 
• 109838-85-9 (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine 

Downstream Products

• 1192674-19-3 (2R,3R)-2-amino-3-hydroxy-3-[(5R)-phenyl-4,5-dihydroisoxazol-3-yl]-propionic acid methyl ester 
• 1192674-20-6 (2R,3R)-[(2R)-(2-amino-3-methyl)-butyrylamino]-3-hydroxy-3-[(5R)-5-phenyl-4,5-dihydroisoxazol-3-yl]-propionic acid methyl ester 

Relevant articles and documents

Enzymatic resolution of (±)-5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester and its transformations into polyfunctionalised amino acids and dipeptides

Enantiomerically pure (5R)-(-)-5-phenyl-4,5-dihydroisoxazole-3-carboxylic acid ethyl ester was obtained via enzymatic resolution of the corresponding racemic mixture using a lipase from hog pancreas (PPL). The following reduction of the ester group to the