1192711-57-1

Basic information

• Product Name: C₁₅H₂₂ClFN₄O₂
• Synonyms: C₁₅H₂₂ClFN₄O₂
• CAS NO: 1192711-57-1
• Molecular Weight: 344.817
• Mol File: 1192711-57-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₂ClFN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₂ClFN₄O₂(1192711-57-1)
• EPA Substance Registry System: C₁₅H₂₂ClFN₄O₂(1192711-57-1)

Safety Data

• Hazardous Substances Data: 1192711-57-1(Hazardous Substances Data)

Upstream product

• 141774-61-0 piperidine-2-yl-methylcarbamic acid tert-butyl ester 
• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 

Downstream Products

• 1192711-58-2 tert-butyl (1-(2-(4-(4-acetylpiperazin-1-yl)phenylamino)-5-fluoropyrimidin-4-yl)piperidin-2-yl)methylcarbamate 

Relevant articles and documents

INHIBITORS OF PROTEIN KINASES

The present invention is directed to compounds of formula (I)-(II) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.