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Featured products 2,4-dichloro-5-fluoropyriMidine( 2927-71-1)
Cas No: 2927-71-1
No Data 100 Gram 1-10 Metric Ton/Month Chemlyte Solutions Contact Supplier
2,4-dichloro- 5-fluoropyrimidine
Cas No: 2927-71-1
No Data 100 Gram 1 Metric Ton/Day China Synchem Technology Co.,Ltd Contact Supplier
2,4-Dichloro-5-fluoropyrimidine with high quality and low price
Cas No: 2927-71-1
No Data No Data Metric Ton/Day Nanjing Fred Technology Co.,Ltd. Contact Supplier
2,4-Dichloro-5-fluoropyrimidine
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USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality 2,4-Dichloro-5-Fluoropyrimidine supplier in China
Cas No: 2927-71-1
No Data 1 Metric Ton 30 Metric Ton/Month Simagchem Corporation Contact Supplier
2,4-Dichloro-5-fluoropyrimidine manufacturer with low price
Cas No: 2927-71-1
No Data 1 Gram 1000 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier
High Quality 99% 2927-71-1 2,4-Dichloro-5-fluoropyrimidine (Abemaci Manufacturer
Cas No: 2927-71-1
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
Factory Supply 2,4-Dichloro-5-fluoropyrimidine
Cas No: 2927-71-1
No Data 1 1 Ality Chemical Corporation Contact Supplier
2,4-Dichloro-5-fluoro-pyrimidine
Cas No: 2927-71-1
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
2,4-Dichloro-5-fluoropyrimidine
Cas No: 2927-71-1
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier

2927-71-1 Usage

Chemical Properties

2,4-Dichloro-5-fluoropyrimidine is Yellow to Orange Crystalline Solid

Uses

2,4-Dichloro-5-fluoropyrimidine is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors. It is used in the synthesis of two glucuronic derivatives of 5-fluorouracil as neoplasm inhibitors.
InChI:InChI=1/C4HCl2FN2/c5-3-2(7)1-8-4(6)9-3/h1H

2927-71-1 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (D3374)  2,4-Dichloro-5-fluoropyrimidine  >98.0%(GC) 2927-71-1 5g 380.00CNY Detail
TCI America (D3374)  2,4-Dichloro-5-fluoropyrimidine  >98.0%(GC) 2927-71-1 25g 1,390.00CNY Detail
Alfa Aesar (H26288)  5-Fluoro-2,4-dichloropyrimidine, 98%    2927-71-1 1g 198.0CNY Detail
Alfa Aesar (H26288)  5-Fluoro-2,4-dichloropyrimidine, 98%    2927-71-1 5g 386.0CNY Detail
Aldrich (653233)  2,4-Dichloro-5-fluoropyrimidine  97% 2927-71-1 653233-1G 1,287.00CNY Detail

2927-71-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,4-Dichloro-5-fluoropyrimidine

1.2 Other means of identification

Product number -
Other names 5-fluoro-2,4-dichloropyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2927-71-1 SDS

2927-71-1Synthetic route

2,4-dimethoxy-5-fluoropyrimidine
4330-22-7

2,4-dimethoxy-5-fluoropyrimidine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Conditions
ConditionsYield
Stage #1: 5-fluoro-2,4-dimethoxypyrimidine With thionyl chloride In chloroform at 0℃; for 0.5h; UV-irradiation;
Stage #2: With chlorine In chloroform at 20℃; for 12h; Solvent; Wavelength; UV-irradiation;
98%
5-fluoropyrimidine-2,4-diol
51-21-8

5-fluoropyrimidine-2,4-diol

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Conditions
ConditionsYield
With trichlorophosphate In N,N-dimethyl-aniline at 100℃; for 13h; Inert atmosphere; Large scale;95%
With pyridine; trichlorophosphate at 180℃; under 150.015 - 900.09 Torr; for 2h; Neat (no solvent);93%
With dimethyl amine; trichlorophosphate at 95 - 120℃; for 4h;92%
5-fluorouracil
51-21-8

5-fluorouracil

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Conditions
ConditionsYield
With dimethyl amine; trichlorophosphate at 95 - 120℃; for 4h;94%
With phosphorus pentachloride for 4h; Heating;91%
Stage #1: 5-fluorouracil With trichlorophosphate at 95℃; for 3.5h;
Stage #2: With hydrogenchloride In water at 0 - 20℃;
87%
2,4,6-trichloro-5-fluoropyrimidine
6693-08-9

2,4,6-trichloro-5-fluoropyrimidine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Conditions
ConditionsYield
With hydrogen; triethylamine; palladium on activated charcoal In ethyl acetate at 30℃; under 2625.2 Torr;87%
ethyl bromide
74-96-4

ethyl bromide

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Conditions
ConditionsYield
With magnesium In tetrahydrofuran
morpholine
110-91-8

morpholine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

4-(2-chloro-5-fluoro-pyrimidin-4-yl)morpholine
31646-53-4

4-(2-chloro-5-fluoro-pyrimidin-4-yl)morpholine

Conditions
ConditionsYield
In water at 60 - 70℃; for 2.5h;100%
With N-ethyl-N,N-diisopropylamine In ethanol Reflux; regioselective reaction;95%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide for 1h; Inert atmosphere; Reflux;85%
piperidine
110-89-4

piperidine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine
40423-82-3

2-chloro-5-fluoro-4-piperidin-1-yl-pyrimidine

Conditions
ConditionsYield
In water at 60 - 70℃; for 2.5h;100%
1-n-propylpiperazine
21867-64-1

1-n-propylpiperazine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-Chloro-5-fluoro-4-(4-propyl-piperazin-1-yl)-pyrimidine

2-Chloro-5-fluoro-4-(4-propyl-piperazin-1-yl)-pyrimidine

Conditions
ConditionsYield
In water at 60 - 70℃; for 2.5h;100%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-chloro-5-fluoropyrimidin-4-amine
155-10-2

2-chloro-5-fluoropyrimidin-4-amine

Conditions
ConditionsYield
With ammonium hydroxide at 60 - 70℃; for 2.5h;100%
With ammonia In water Substitution;
With ammonium hydroxide In ethanol at 25 - 35℃; for 3.5h;
(R)-tert-butyl (1-aminobutan-2-yl)carbamate
956125-05-6

(R)-tert-butyl (1-aminobutan-2-yl)carbamate

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

{(R)-1-[(2-Chloro-5-fluoro-pyrimidin-4-ylamino)-methyl]-propyl}-carbamic acid tert-butyl ester
956125-24-9

{(R)-1-[(2-Chloro-5-fluoro-pyrimidin-4-ylamino)-methyl]-propyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With triethylamine In acetonitrile at 0℃; for 3h;100%
4-methoxy-aniline
104-94-9

4-methoxy-aniline

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

5-fluoro-N2,N4-bis(4-methoxyphenyl)pyrimidine-2,4-diamine diformate

5-fluoro-N2,N4-bis(4-methoxyphenyl)pyrimidine-2,4-diamine diformate

Conditions
ConditionsYield
Stage #1: 4-methoxy-aniline; 2,4-dichloro-5-fluoropyrimidine With N-ethyl-N,N-diisopropylamine In 1,4-dioxane at 160℃; for 0.333333h; Microwave irradiation;
Stage #2: With formic acid In water; acetonitrile
100%
4-fluoroboronic acid
1765-93-1

4-fluoroboronic acid

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine
1341200-71-2

2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine

Conditions
ConditionsYield
With palladium diacetate; sodium carbonate; triphenylphosphine In tetrahydrofuran; water for 12h; Suzuki coupling; Reflux;100%
(S)-1-(1-methyl-6-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanamine
1537256-09-9

(S)-1-(1-methyl-6-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

(S)-2-chloro-5-fluoro-N-(1-(1-methyl-6-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl)pyrimidin-4-amine
1537207-28-5

(S)-2-chloro-5-fluoro-N-(1-(1-methyl-6-(1-methyl-1H-pyrazol-5-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl)ethyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 120℃; for 1h; Microwave irradiation;100%
n-propylmagnesium bromide
927-77-5

n-propylmagnesium bromide

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2,4-dichloro-5-fluoro-6-propylpyrimidine

2,4-dichloro-5-fluoro-6-propylpyrimidine

Conditions
ConditionsYield
Stage #1: n-propylmagnesium bromide; 2,4-dichloro-5-fluoropyrimidine In tetrahydrofuran; 1,2-dimethoxyethane at 15℃; for 1h;
Stage #2: With iodine; triethylamine In tetrahydrofuran; 1,2-dimethoxyethane at 5℃;
100%
cyclopropanol
16545-68-9

cyclopropanol

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-chloro-4-cyclopropoxy-5-fluoropyrimidine

2-chloro-4-cyclopropoxy-5-fluoropyrimidine

Conditions
ConditionsYield
Stage #1: cyclopropanol With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.333333h;
Stage #2: 2,4-dichloro-5-fluoropyrimidine In tetrahydrofuran; mineral oil at 0℃; for 4h;
100%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

4-fluoroaniline
371-40-4

4-fluoroaniline

2-chloro-5-fluoro-N-(4-fluorophenyl)pyrimidin-4-amine
1049666-34-3

2-chloro-5-fluoro-N-(4-fluorophenyl)pyrimidin-4-amine

Conditions
ConditionsYield
With trifluoroacetic acid In ethanol at 20℃; for 24h; regioselective reaction;99%
In methanol; water at 50℃; for 5h;68%
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 80℃; for 1.5h;
Nα-isobutyl-Nβ-Boc-hydrazine
57699-53-3

Nα-isobutyl-Nβ-Boc-hydrazine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

C13H20ClFN4O2
929016-08-0

C13H20ClFN4O2

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol Reflux;99%
7-fluoro-2,3,3-trimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole

7-fluoro-2,3,3-trimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-indole

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

5-(2-chloro-5-fluoropyrimidin-4-yl)-7-fluoro-2,3,3-trimethyl-3H-indole

5-(2-chloro-5-fluoropyrimidin-4-yl)-7-fluoro-2,3,3-trimethyl-3H-indole

Conditions
ConditionsYield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 130℃; for 1h; Suzuki Coupling; Inert atmosphere; Microwave irradiation;99%
With tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 130℃; for 1h; Microwave irradiation; Inert atmosphere;301.2 mg
2-pyridylmethyl 4-tolyl sulfone
58414-96-3

2-pyridylmethyl 4-tolyl sulfone

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-Chloro-10-(toluene-4-sulfonyl)-pyrimido[4,5-b]indolizine
137890-00-7

2-Chloro-10-(toluene-4-sulfonyl)-pyrimido[4,5-b]indolizine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide Heating;98%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

2-methyl-2-(2-chloro-5-fluoropyrimidinyl-4-yl)-1,3-propanedioic acid diethyl ester
137234-89-0

2-methyl-2-(2-chloro-5-fluoropyrimidinyl-4-yl)-1,3-propanedioic acid diethyl ester

Conditions
ConditionsYield
Stage #1: Diethyl methylmalonate With sodium hydride In tetrahydrofuran; mineral oil at -10℃; for 0.5h;
Stage #2: 2,4-dichloro-5-fluoropyrimidine In tetrahydrofuran; mineral oil at -10℃; for 0.5h;
98%
With sodium hydride In tetrahydrofuran; mineral oil at -10℃; for 0.5h;83%
1-(4-{4-amino-3-methoxyphenyl}piperazine-1-yl)ethan-1-one
1021426-42-5

1-(4-{4-amino-3-methoxyphenyl}piperazine-1-yl)ethan-1-one

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

1-(4-(4-((2-chloro-5-fluoropyrimidin-4-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethanone
1474014-16-8

1-(4-(4-((2-chloro-5-fluoropyrimidin-4-yl)amino)-3-methoxyphenyl)piperazin-1-yl)ethanone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50℃; Temperature;98%
With potassium carbonate In N,N-dimethyl-formamide at 80℃;68%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole
847818-74-0

1-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole

2-chloro-5-fluoro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

2-chloro-5-fluoro-4-(1-methyl-1H-pyrazol-5-yl)pyrimidine

Conditions
ConditionsYield
With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate In tetrahydrofuran; water Reflux;98%
N-(1,3-benzodioxol-5-ylmethyl)-2-(tetrahydro-2H-pyran-4-yl)ethanamine

N-(1,3-benzodioxol-5-ylmethyl)-2-(tetrahydro-2H-pyran-4-yl)ethanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]pyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[2-(tetrahydro-2H-pyran-4-yl)ethyl]pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 85℃;98%
methyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride

methyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

methyl 6-(2-chloro-5-fluoropyrimidin-4-yl)-6-azaspiro[2.5]octane-1-carboxylate

methyl 6-(2-chloro-5-fluoropyrimidin-4-yl)-6-azaspiro[2.5]octane-1-carboxylate

Conditions
ConditionsYield
With triethylamine In methanol at 30℃; for 16h;98%
3-methyl-5-aminopyrazole
31230-17-8

3-methyl-5-aminopyrazole

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

2-chloro-5-fluoro-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine
851434-99-6

2-chloro-5-fluoro-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine

Conditions
ConditionsYield
With triethylamine In ethanol at 0 - 25℃; regioselective reaction;97%
With N-ethyl-N,N-diisopropylamine In ethanol at 20℃; for 48h; Inert atmosphere;86%
With N-ethyl-N,N-diisopropylamine In ethanol at 20℃; for 48h; Inert atmosphere;86%
With triethylamine In ethanol at 18 - 25℃; for 12h;
With triethylamine In ethanol at 18 - 25℃; for 12h;
2-fluorobenzylamine
89-99-6

2-fluorobenzylamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

(2-chloro-5-fluoropyrimidin-4-yl)-(2-fluorobenzyl)amine
1174385-80-8

(2-chloro-5-fluoropyrimidin-4-yl)-(2-fluorobenzyl)amine

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 5h; Reflux;97%
With triethylamine In tetrahydrofuran at 80℃; for 5h;97%
N-(1,3-benzodioxol-5-ylmethyl)-3-(5-phenyl-1,2,4-oxadiazol-3-yl)propan-1-amine

N-(1,3-benzodioxol-5-ylmethyl)-3-(5-phenyl-1,2,4-oxadiazol-3-yl)propan-1-amine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[3-(5-phenyl-1,2,4-oxadiazol-3-yl)propyl]pyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[3-(5-phenyl-1,2,4-oxadiazol-3-yl)propyl]pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 85℃;97%
tert-butyl 3-hydroxyphenylcarbamate
19962-06-2

tert-butyl 3-hydroxyphenylcarbamate

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

C15H15ClFN3O3
1246610-46-7

C15H15ClFN3O3

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In butan-1-ol at 110℃; for 16h;96%
2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

sodium thiomethoxide
5188-07-8

sodium thiomethoxide

2-chloro-5-fluoro-4-methylthiopyrimidine

2-chloro-5-fluoro-4-methylthiopyrimidine

Conditions
ConditionsYield
In tetrahydrofuran at -30℃; for 2h;96%
In tetrahydrofuran; water at -30℃; for 2h;93%
In tetrahydrofuran at 20℃; for 12h;
N-(1,3-benzodioxol-5-ylmethyl)-1-methylcyclopropanamine

N-(1,3-benzodioxol-5-ylmethyl)-1-methylcyclopropanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-(1-methylcyclopropyl)pyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-(1-methylcyclopropyl)pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 85℃;96%
N-(1,3-benzodioxol-5-ylmethyl)-2-(4-fluorophenyl)ethanamine

N-(1,3-benzodioxol-5-ylmethyl)-2-(4-fluorophenyl)ethanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[2-(4-fluorophenyl)ethyl]pyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-5-fluoro-N-[2-(4-fluorophenyl)ethyl]pyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 85℃;96%
1-(1,3-benzodioxol-5-yl)-N-(cyclopropylmethyl)methanamine

1-(1,3-benzodioxol-5-yl)-N-(cyclopropylmethyl)methanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-N-(cyclopropylmethyl)-5-fluoropyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-N-(cyclopropylmethyl)-5-fluoropyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol; isopropyl alcohol at 85℃;96%
N-(1,3-benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)ethanamine

N-(1,3-benzodioxol-5-ylmethyl)-2-(4-chloro-3,5-dimethylphenoxy)ethanamine

2,4-dichloro-5-fluoropyrimidine
2927-71-1

2,4-dichloro-5-fluoropyrimidine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-N-[2-(4-chloro-3,5-dimethylphenoxy)ethyl]-5-fluoropyrimidin-4-amine

N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-N-[2-(4-chloro-3,5-dimethylphenoxy)ethyl]-5-fluoropyrimidin-4-amine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 85℃;96%

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