1192712-34-7

Basic information

• Product Name: benzyl (1s,4s)-4-(2-chloro-5-fluoropyrimidin-4-ylamino)cyclohexylcarbamate
• Synonyms: benzyl (1s,4s)-4-(2-chloro-5-fluoropyrimidin-4-ylamino)cyclohexylcarbamate
• CAS NO: 1192712-34-7
• Molecular Weight: 378.834
• Mol File: 1192712-34-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (1s,4s)-4-(2-chloro-5-fluoropyrimidin-4-ylamino)cyclohexylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (1s,4s)-4-(2-chloro-5-fluoropyrimidin-4-ylamino)cyclohexylcarbamate(1192712-34-7)
• EPA Substance Registry System: benzyl (1s,4s)-4-(2-chloro-5-fluoropyrimidin-4-ylamino)cyclohexylcarbamate(1192712-34-7)

Safety Data

• Hazardous Substances Data: 1192712-34-7(Hazardous Substances Data)

Upstream product

• 149423-70-1 (±)-cis-N1-benzyloxycarbonyl-1,4-cyclohexanediamine 
• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 

Downstream Products

• 1192712-35-8 C₂₇H₂₉FN₆O₃ 

Relevant articles and documents

INHIBITORS OF PROTEIN KINASES

The present invention is directed to compounds of formula (I)-(II) and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.