119273-16-4

Upstream product

• 82206-88-0 (11S)-3α-hydroxy-11β-(phenylseleno)guaia-4(15),10(14)-dieno-12,6α-lactone 
• 64-19-7 acetic acid 
• 38236-17-8 isocostus lactone 
• 1666-13-3 diphenyl diselenide 
• 82207-06-5 (11S)-3α-(mesyloxy)-4βH-guai-10(14)-en-13,6α-lactone 
• 67721-76-0 (11S)-3α,4α-epoxy-1β-(mesyloxy)eudesmano-13,6α-lactone 
• 67895-33-4 (11S)-3α-(benzoyloxy)-4βH-guai-10(14)-eno-13,6α-lactone 
• 67895-32-3 Benzoic acid (3S,3aS,5aR,6R,8R,9R,9aS,9bS)-6-methanesulfonyloxy-3,5a,9-trimethyl-2-oxo-dodecahydro-naphtho[1,2-b]furan-8-yl ester 
• 481-06-1 santonin 
• 82263-12-5 (+)-3α,4α-epoxy-1,5,7αH,6,11βH-guai-1(14)-en-6,12-olide 
• 82207-05-4 (11S)-3α-hydroxy-4βH-guai-10(14)-en-13,6α-lactone 
• 82206-87-9 3α-hydroxy-11βH-guaia-4(15),10(14)-diene-12,6α-olide 

Downstream Products

• 82206-97-1 3β-hydroxy-11β-(phenylseleno)guaia-4(15),10(14)-dieno-12,6α-lactone 

Relevant academic research and scientific papers

Studies on the Syntheses of Sesquiterpene Lactones. 11. The Syntheses of 3-Epizaluzanin C, Zaluzanin C, Zaluzanin D, and Related Compounds 3&α-Hydroxyguaia-1(10),4(15),11(13)-trieno-12,6&α-lactone and 3&α-Hydroxyguaia-4(15),9,11(13)-trieno-12,6&α-lactone

3-Epizaluzanin C (10), 3α-hydroxyguaia-1(10),4(15),11(13)-trieno-12,6α-lactone (36), and 3α-hydroxyguaia-4(15),9,11(13)-trieno-12,6α-lactone (37) have been synthesized in 4.0percent, 3.0percent, and 1.7percent overall yields, respectively, from α-santonine (13) in 14 steps.Zaluzanin C (11) and zaluzanin D (12) have also been synthesized in 2.4percent and 2.5percent overall yields from α-santonin (13) in 16 steps and 15 steps, respectively.The key step involves the solvolytic rearrangement of (11S)-3α,4α-epoxy-1β-(mesyloxy)eudesmano-13,6α-lactone (27).The stereochemistry of3-epizaluzanin C (10), zaluzanin C (11), and zaluzanin D (12) have been established by these stereospecific syntheses.