1192743-76-2Relevant academic research and scientific papers
Recyclable catalytic synthesis of substituted quinolines: copper-catalyzed heterocyclization of 1-(2-aminoaryl)-2-yn-1-ols in ionic liquids
Gabriele, Bartolo,Mancuso, Raffaella,Lupinacci, Elvira,Spina, Rosella,Salerno, Giuseppe,Veltri, Lucia,Dibenedetto, Angela
, p. 8507 - 8512 (2009)
A convenient and simple approach for the recyclable catalytic synthesis of substituted quinolines is presented. The method is based on CuCl2-catalyzed heterocyclization of readily available 1-(2-aminoaryl)-2-yn-1-ols in BmimBF4 as the solvent at 100 °C for 15-24 h. The solvent-catalyst system could be successfully recycled up to six times without significant loss of activity.
