1192966-53-2

Basic information

• Product Name: tert-butyl (1-phenylbut-3-yn-1-yl)carbamate
• Synonyms: tert-butyl (1-phenylbut-3-yn-1-yl)carbamate
• CAS NO: 1192966-53-2
• Molecular Weight: 245.321
• Mol File: 1192966-53-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl (1-phenylbut-3-yn-1-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1-phenylbut-3-yn-1-yl)carbamate(1192966-53-2)
• EPA Substance Registry System: tert-butyl (1-phenylbut-3-yn-1-yl)carbamate(1192966-53-2)

Safety Data

• Hazardous Substances Data: 1192966-53-2(Hazardous Substances Data)

Upstream product

• 106-96-7 propargyl bromide 
• 150884-50-7 benzaldehyde N-boc imine 
• 865350-17-0 4,4,5,5-tetramethyl-2-(propa-1,2-dien-1-yl)-1,3,2-dioxaborolane 
• 67-56-1 methanol 
• 374725-03-8 tert-butyl (-formyl-1-phenylethyl)carbamate 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 

Downstream Products

• 82745-22-0 1-phenyl-1-amino-3-butyne 

Relevant articles and documents

Redox Economic Synthesis of TrisubstitutedPiperidones via Ruthenium Catalyzed Atom-Economic Couplings of N-Protected 1,5-Aminoalcohols and Michael Acceptors

An efficient atom-economic coupling of 1,5-amino alcohols and Michael acceptors has been developed employing [CpRu(MeCN)3]PF6 as a key catalyst to synthesize α,β-unsaturated ketones with exclusive generation of E-geometrical isomers at room temperature without any co-catalyst and additives. A base catalysed 6-endo-trig cyclization of the α,β-unsaturated ketone delivers a direct access to tri-substituted piperidones.

ALPHA2B AND ALPHA2C AGONISTS

Described herein are compounds that can be useful as bioactive agents. More specifically, the compounds described herein can be useful as both α2B and α2C adrenergic agonists. Methods of synthesis and administration of the compounds are also disclosed.