119318-15-9

Usage

Uses

Used in Pharmaceutical Industry:
Olean-12-ene-3,24-diol is used as a therapeutic agent for its potential anti-inflammatory and antioxidant properties, which may contribute to the treatment of various inflammatory and oxidative stress-related conditions.
Used in Anticancer Applications:
Olean-12-ene-3,24-diol is used as an anticancer agent, as it has been examined for its potential to inhibit cancer cell growth and proliferation. It may be employed in the development of novel cancer treatments or as an adjunct to existing therapies.
Used in Anti-diabetic Applications:
Olean-12-ene-3,24-diol is used as an anti-diabetic agent, as it has been studied for its potential to improve insulin sensitivity and glucose metabolism. It may be utilized in the development of treatments for diabetes and related metabolic disorders.
Used in Nutraceutical Industry:
Olean-12-ene-3,24-diol is used as a nutraceutical ingredient for its potential health benefits, including its anti-inflammatory, antioxidant, and potential anti-cancer and anti-diabetic properties. It may be incorporated into dietary supplements and functional foods to promote overall health and well-being.

Upstream product

• 1318059-50-5 24-hydroxyolean-12-en-3β-yl-β-D-glucopyranoside 
• 195156-10-6 C₄₀H₆₀O₅S 
• 104235-58-7 22β-hydroxy-3β,24-isopropylidenedioxyolean-12-ene 
• 104235-76-9 C₃₃H₅₂O₃ 
• 186415-72-5 C₃₃H₅₂O₂ 
• 64-17-5 ethanol 
• 595-14-2 soyasapogenol C 
• 195156-19-5 3β-hydroxy-olean-12-en-24-oic acid methyl ester 
• 135322-63-3 24-hydroxyolean-12-en-3-one 

Downstream Products

• 50-00-0 formaldehyd 
• 195156-11-7 24-trityloxyolean-12-en-3β-ol 
• 559-70-6 beta-amyrin 
• 195156-12-8 3β-benzoyloxy-24-trityloxyolean-12-ene 
• 195156-13-9 Benzoic acid (3S,4S,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-4-hydroxymethyl-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-picen-3-yl ester 
• 195156-14-0 3β-benzoyloxy-24-oxoolean-12-ene 

Relevant academic research and scientific papers

TRITERPENOIDS FROM SYMPLOCOS RACEMOSA BARK

Three new triterpenes have been isolated from the stem bark of Symplocos racemosa together with the two known triterpenoids betulin and oleanolic acid.Their structures were characterized as 28-hydroxy-20α-urs-12,18(19)-dien-3β-yl acetate, 3-oxo-urs-20α-12,18(19)-dien-28-oic acid and 24-hydroxyolean-12-en-3-one by spectral and chemical means.

Triterpenes from the Leaves of Parsonsia Laevigata

A novel taraxerane-type triterpene-diol, in addition to taraxerol and lupeol, was isolated from the leaves of Parsonsia laevigata.Its structure was shown to be (4β)-D-friedoolean-14-ene-3β,24-diol (taraxer-14-ene-3β,24-diol) by a combination of chemical and spectroscopic methods.Key Word Index - Parsonsia laevigata; Apocynaceae; taraxerane-type triterpenoid; (4β)-D-friedoolean-14-ene-3β,24-diol.

Triterpenoid derivatives from Cylicodiscus gabunensis

Three new olean-12-ene derivatives (1-3), together with known urs-12-ene-3β, 28-diol (4) were isolated from the stem root of Cylicodiscus gabunensis. The structures of the new compounds were established by chemical and spectroscopic means as β-amyrin-n-no

Preventive effects of soyasapogenol B derivatives on liver injury in a concanavalin A-induced hepatitis model

To shed light on the structure-activity relationship, various soyasapogenol B derivatives were synthesized and evaluated for preventive effects on liver injury in the concanavalin A (Con A)-induced hepatitis model in mice. Con A injection into mice induces some pathophysiology of human liver disease such as autoimmune or viral hepatitis. Two hydroxyl groups on the A ring of soyasapogenol B are required for amelioration of liver damage. Modification of the C-22 hydroxyl moiety with an acyloxy or alkyloxy group, or removal of the hydroxyl group, resulted in a greatly enhanced percentage of alleviation. Among the series of soyasapogenol B derivatives examined, six compounds exhibited preventive effects on liver damage.

Synthesis and hepatoprotective effects of soyasapogenol B derivatives

Derivatives of soyasapogenol B (1), which is the aglycon moiety of soyasaponins from soybean, were synthesized and evaluated for their hepatoprotective effects in vitro.