1193397-35-1Relevant academic research and scientific papers
Reduction alcoholization and resolution method of cyclohexyl phenyl ketone
-
, (2017/08/27)
The invention discloses a reduction alcoholization and resolution method of cyclohexyl phenyl ketone. The reduction alcoholization and resolution method takes the cyclohexyl phenyl ketone as a raw material; the cyclohexyl phenyl ketone is subjected to hyd
Empirical method for predicting enantioselectivity in catalytic reactions: demonstration with lipase and oxazaborolidine
Ema, Tadashi,Ura, Norichika,Yoshii, Masataka,Korenaga, Toshinobu,Sakai, Takashi
supporting information; experimental part, p. 9583 - 9591 (2010/01/06)
We derived a novel equation capable of predicting the degree of enantioselectivity in a catalytic reaction without any knowledge of the reaction mechanism and/or the transition-state structure, and tested the validity of this equation by changing substrates systematically in the lipase or oxazaborolidine-catalyzed reactions. A good correlation was observed between the predicted and observed E values, and the stereochemistry of the products could be predicted correctly in most cases (28 out of 30).
