1193683-64-5

Upstream product

• 1823-91-2 1-phenylethyl cyanide 
• 104367-49-9 2-methyl-2-phenylpent-4-enenitrile 
• 98-59-9 p-toluenesulfonyl chloride 
• 399559-66-1 2-methyl-2-phenyl-4-pentenyl-1-amine 

Downstream Products

• 1193683-76-9 C₁₉H₂₃NO₂S 

Relevant academic research and scientific papers

Copper-Catalyzed Carbonylative Synthesis of β-Homoprolines from N-Fluoro-sulfonamides

A new methodology for the carbonylative transformation of N-fluoro-sulfonamides into N-sulfonyl-β-homoproline esters has been described. In the presence of a catalytic amount of Cu(OTf)2, a range of β-homoproline derivatives were prepared in moderate to good yield. The reaction proceeds via the intramolecular cyclization and intermolecular carbonylation of a free carbon radical. Notably, this procedure offers the possibility to build potential functionalized bioactive molecules.