119392-35-7Relevant academic research and scientific papers
Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol
Merrer, Yves Le,Gravier-Pelletier, Christine,Micas-Languin, Dominique,Mestre, Francoise,Dureault, Annie,Depezay, Jean-Claude
, p. 2409 - 2416 (2007/10/02)
A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re
GLYCALS IN STEREOSPECIFIC SYNTHESIS. II. DI-O-BENZYL-L-ARABINAL AND DI-O-BENZOYL-L-ARABINAL IN THE SYNTHESIS OF SATURATED AND UNSATURATED TERMINAL EPOXIDES
Tolstikov, A. G.,Khakhalina, N. V.,Savateeva, E. E.,Spirikhin, L. V.,Odinokov, V. N.,Tolstikov, G. A.
, p. 706 - 710 (2007/10/02)
The acid opening of di-O-benzyl-L-arabinal and di-O-benzoyl-L-arabinal, catalyzed by mercuric sulfate, is the key stage in the synthesis of chiral dihydroxy compounds with selectively protected hydroxy functions.They were used for the production of saturated and unsaturated terminal epoxides, which are of potential interest as chiral units in the convergent synthesis of biologically active compounds.
