1194057-62-9

Basic information

• Product Name: (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl
• Synonyms: (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl;Benzyl ((3R,5S)-5-(hydroxyMethyl)pyrrolidin-3-yl)carbaMate hydrochloride
• CAS NO: 1194057-62-9
• Molecular Formula: C₁₃H₁₈N₂O₃*ClH
• Molecular Weight: 286.75456
• Mol File: 1194057-62-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl(1194057-62-9)
• EPA Substance Registry System: (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl(1194057-62-9)

Safety Data

• Hazardous Substances Data: 1194057-62-9(Hazardous Substances Data)

Usage

Description

(2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl, with the molecular formula C13H21ClN2O3, is a hydrochloride salt of an amino pyrrolidine compound. It features a hydroxymethyl group and a carbobenzyloxy (CBZ) functional group attached to the amino group. This chiral compound serves as a potential intermediate in the synthesis of various pharmaceuticals and is widely utilized in organic chemistry research and drug development. It also demonstrates potential as a chiral building block in the creation of biologically active molecules. (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl exhibits moderate solubility in water and can be stored at room temperature.

Uses

Used in Pharmaceutical Industry:
(2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Organic Chemistry Research:
In the field of organic chemistry, (2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl is employed as a chiral building block, facilitating the synthesis of biologically active molecules with potential applications in medicine and other areas.
Used in Drug Development:
(2S,4R)-2-hydroxyMethyl-4-CBZ-aMino Pyrrolidine-HCl is utilized in drug development for its potential to enhance the properties of new drug candidates, contributing to improved efficacy and selectivity in targeted therapies.

Upstream product

• 1194057-63-0 (2S,4R)-tert-butyl 4-(benzyloxycarbonylamino)-2-(hydroxymethyl)pyrrolidine-1-carboxylate 

Downstream Products

• 1194057-64-1 ethyl 7-((2S,4R)-4-benzyloxycarbonylamino-2-(hydroxymethyl)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-fomyl-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 1194057-65-2 ethyl 7-((2S,4R)-4-benzyloxycarbonylamino-2-(hydroxymethyl)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-8-hydroxymethyl-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 1194057-67-4 ethyl (3aS,5R)-5-benzyloxycarbonylamino-13-cyclopropyl-8-fluoro-10-oxo-3a,4,5,6,10,13-hexahydro-1H,3H-pyrrolo[2',1':3,4][1,4]oxazepino[5,6-h]quinoline-11-carboxylate 

Relevant articles and documents

ANTIBACTERIAL FLUOROQUINOLONE ANALOGS

Compounds having antibacterial activity are disclosed. The compunds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, D, E, G, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.