1194096-64-4

Upstream product

• 154731-80-3 (R)-2-tert-butoxycarbonylamino-3,3-dicyclohexyl-propionic acid 
• 1447671-77-3 5-(aminomethyl)pyridin-2-amine dihydrochloride 
• 143060-31-5 N-(tert-butoxycarbonyl)-3,3-diphenyl-D-alanine 
• 4214-73-7 6-aminonicotinonitrile 

Downstream Products

• 1300006-88-5 N-{(R)-1-[(6-amino-pyridin-3-ylmethyl)-carbamoyl]-2,2-dicyclohexyl-ethyl}-2-hydroxy-2-methyl-propionamide trifluoroacetate 
• 1194096-67-7 ((S)-1-[(R)-1-[(6-amino-pyridin-3-ylmethyl)-carbamoyl]-2,2-dicyclohexyl-ethylcarbamoyl]-2-methylbutyl)carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (such as asthma or COPD); and methods of treating patients with such compounds; wherein R1 - R10 and A1 are as defined herein.

AMINOPYRIDINE DERIVATIVES

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (such as asthma or COPD); and methods of treating patients with such compounds; wherein R1 - R11 ar