Cas 1194097-24-9,(S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide

1194097-24-9

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Basic information

Product Name: (S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide
Synonyms: (S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide
CAS NO:1194097-24-9
Molecular Formula:
Molecular Weight: 514.971
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide(CAS DataBase Reference)
NIST Chemistry Reference: (S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide(1194097-24-9)
EPA Substance Registry System: (S)-1-acryloyl-N-[4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-6-yl]azetidine-2-carboxamide(1194097-24-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1194097-24-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1194097-24-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,4,0,9 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1194097-24:
(9*1)+(8*1)+(7*9)+(6*4)+(5*0)+(4*9)+(3*7)+(2*2)+(1*4)=169
169 % 10 = 9
So 1194097-24-9 is a valid CAS Registry Number.

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1194097-24-9Relevant academic research and scientific papers

Discovery of a novel Her-1/Her-2 dual tyrosine kinase inhibitor for the treatment of Her-1 selective inhibitor-resistant non-small cell lung cancer

Mi, Young Cha,Lee, Kwang-Ok,Jong, Woo Kim,Chang, Gon Lee,Ji, Yeon Song,Young, Hoon Kim,Gwan, Sun Lee,Seung, Bum Park,Maeng, Sup Kim

, p. 6880 - 6888 (2009)

A novel series of (S)-1-acryloyl-N-[4-(arylamino)-7-(alkoxy)quinazolin-6- yl]pyrrolidine-2-carboxamides were synthesized and evaluated as Her-1/Her-2 dual inhibitors. In contrast to the Her-1 selective inhibitors, our novel compounds are irreversible inhi

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