1194376-31-2 Usage
General Description
Tert-butyl 3-cyano-3-hydroxypyrrolidine-1-carboxylate is a chemical compound with the molecular formula C10H16N2O3. It is a pyrrolidine derivative that is commonly used in organic synthesis as a building block for the preparation of various pharmaceutical and agrochemical compounds. The tert-butyl group at the 3-position of the pyrrolidine ring increases its stability and makes it a useful intermediate for the synthesis of complex organic molecules. The presence of the cyano and hydroxyl groups in the chemical structure also makes it a versatile starting material for the preparation of different types of compounds. Furthermore, the carboxylate group adds polarity to the molecule, making it useful for reactions involving the formation of amide or ester bonds. Overall, tert-butyl 3-cyano-3-hydroxypyrrolidine-1-carboxylate is a valuable chemical building block with a wide range of applications in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1194376-31-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,4,3,7 and 6 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1194376-31:
(9*1)+(8*1)+(7*9)+(6*4)+(5*3)+(4*7)+(3*6)+(2*3)+(1*1)=172
172 % 10 = 2
So 1194376-31-2 is a valid CAS Registry Number.
1194376-31-2Relevant articles and documents
COMPOUNDS USEFUL AS IMMUNOMODULATORS
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Paragraph 0452; 0453; 0454; 0455, (2017/05/07)
The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
Bespoke SnAP reagents for the synthesis of c-substituted spirocyclic and bicyclic saturated N-heterocycles
Geoghegan, Kimberly,Bode, Jeffrey W.
supporting information, p. 1934 - 1937 (2015/04/27)
The precise placement of C-substituents on bicyclic and spirocyclic N-heterocycles is readily achieved by the combination of aldehydes and new SnAP reagents. The substituted SnAP reagents are readily prepared from simple starting materials and couple with
Spiro-rifamycin derivatives targeting RNA polymerase
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Page/Page column 20, (2008/06/13)
Compounds of the current invention relate to rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms. More specifically, compounds of the current invention relate to a series of novel spiro rifamycin derivatives which have demonstrated potent antimicrobial activity.