119477-85-9 Usage
Uses
Used in Pharmaceutical Industry:
U-75302 is used as a selective leukotriene B4 antagonist for targeting the BLT1 receptor. This selective antagonism can be beneficial in the development of drugs that modulate leukotriene B4 signaling pathways, which play a crucial role in various inflammatory and immune responses.
Used in Inflammatory Disease Treatment:
U-75302 is used as a therapeutic agent for treating inflammatory diseases by selectively blocking the BLT1 receptor. This can help in reducing inflammation and managing symptoms associated with conditions such as rheumatoid arthritis, inflammatory bowel disease, and other autoimmune disorders.
Used in Immunological Research:
U-75302 is used as a research tool for studying the role of leukotriene B4 and its receptors in immune system regulation. By selectively antagonizing the BLT1 receptor, researchers can gain insights into the molecular mechanisms underlying leukotriene B4-mediated immune responses and develop targeted therapies for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 119477-85-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,4,7 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 119477-85:
(8*1)+(7*1)+(6*9)+(5*4)+(4*7)+(3*7)+(2*8)+(1*5)=159
159 % 10 = 9
So 119477-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H35NO3/c1-2-3-4-5-6-7-13-21(25)16-15-19-11-10-12-20(23-19)18-22(26)14-8-9-17-24/h6-7,10-12,15-16,21-22,24-26H,2-5,8-9,13-14,17-18H2,1H3/b7-6-,16-15+/t21-,22+/m1/s1
119477-85-9Relevant academic research and scientific papers
SYNTHESIS OF NOVEL ANTAGONISTS OF LEUKOTRIENE B4
Morris, Joel,Wishka, Donn G.
, p. 143 - 146 (2007/10/02)
As part of a program to identify a stable LTB4 antagonist, several novel compounds containing a 2,6-disubstituted pyridine ring in place of carbons 7-9 of the natural eicosanoid were synthesized utilizing a Pd-Cu cross coupling reaction.
