119478-96-5Relevant academic research and scientific papers
Biomimetic synthesis: Discovery of xanthanolide dimers
Shang, Hai,Liu, Junhua,Bao, Ruiyang,Cao, Yu,Zhao, Kun,Xiao, Chengqian,Zhou, Bing,Hu, Lihong,Tang, Yefeng
, p. 14494 - 14498 (2014)
Starting from xanthatin, the biomimetic synthesis of 4b,5b-epoxyxanthatin-1a,4a-endoperoxide, a novel monomeric xanthanolide, has been achieved. Moreover, four unprecedented xanthanolide dimers were synthesized by three different dimerizations of xanthatin, either in a head-tohead or head-to-tail fashion. Notably, these dimeric compounds were firstly identified as artifacts in the laboratory, and two of them, mogolides A and B, proved to be natural products present in the Xanthium mogolium Kitag plant.
Asymmetric total syntheses of xanthatin and 11,13-dihydroxanthatin using a stereocontrolled conjugate allylation to γ-butenolide
Matsumoto, Kenji,Koyachi, Kuniyoshi,Shindo, Mitsuru
, p. 1043 - 1049 (2013/02/23)
The stereocontrolled conjugate allylation to an optically pure γ-butenolide provided direct and reliable access to a trans-fused series of xanthanolide sesquiterpenoids and allowed for the enantioselective total syntheses of xanthatin and 11,13-dihydroxanthatin to be efficiently achieved.
