119493-02-6Relevant articles and documents
Synthesis of 4-Unsubstituted β-Lactams via Dithiocarbonimidates
Sharma, S. D.,Mehra, Usha,Khurana, J. P. S.,Pandhi, S. B.
, p. 990 - 992 (2007/10/02)
Cycloaddition of dithiocarbonimidate 1 to the ketene generated in situ from phenoxyacetylchloride in the presence of triethylamine affords the 4-dithioalkyl-2-azetidinones 2 in good yields.Facile conversion of 2 to the 4-unsubstituted β-lactams 3 can be accomplished by desulfurization with Raney-Nickel.Formation of several interesting products during attempts to bring a carbonyl function at C-4 in 2 has also been described.