119514-71-5Relevant academic research and scientific papers
Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
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, (2008/06/13)
Substituted imidazolyl-alkyl-piperazine and diazepine derivatives of Formula A: STR1 wherein: R 1 is aryl, lower alkyl, cycloalkyl or hydrogen;R 2 is aryl, lower alkyl or hydrogen;R 3 is lower alkyl, hydroxy, or hydrogen;R 4 is aryl or hydrogen;R 5 is aryl or hydrogen;m is two or three;n is zero, one or two,provided that when R 3 is hydroxy, n is one or two; andq is zero, one, two, or three;and the pharmaceutically acceptable salts thereof, are calcium channel antagonists useful for treating mammals having a variety of disease states, such as stroke, epilepsy, hypertension, angina, migraine, arrhythmia, thrombosis, embolism and also for treatment of spinal injuries.
