119548-54-8Relevant academic research and scientific papers
Synthesis of piperidine derivatives by reduction of pyridinium salts
Tang, Zilong,Mayrargue, Joelle,Alami, Mouad
, p. 3367 - 3379 (2008/02/13)
Piperidine derivatives 1a-e and 2a-f have been prepared by the reduction of 3-and 4-substituted pyridinium salts with NaBH4 in moderate to excellent yields. The reactions regioselectively give 1,2,5,6-tetrahydropyridines, and the yields depend greatly upon the nature of substituents on the phenyl ring and on the nitrogen atom, the nature and the position of the substituents on the pyridyl ring, and the chain length between the aryloxy and the pyridyl groups. Copyright Taylor & Francis Group, LLC.
Intramolecular Heck-type reactions in aqueous medium. Dramatic change in regioselectivity
Lemaire-Audoire, Sandrine,Savignac, Monique,Dupuis, Christophe,Genet, Jean-Pierre
, p. 2003 - 2006 (2007/10/03)
Efficient intramolecular Heck-type cyclizations were carried out in aqueous medium using water-soluble Pd/TPPTS catalysts. Under these conditions, the generally observed exo process was reversed in favor of the regioselective formation of endo cyclized co
RHODIUM (1) CATALYSED REGIOSPECIFIC CYCLISATION OF 1,6-ENYNES TO METHYLENECYCLOHEX-2-ENES
Grigg, Ronald,Stevenson, Paul,Worakun, Tanachat
, p. 4967 - 4972 (2007/10/02)
1,6-Enynes are cyclised regiospecifically by 5 mol percent of Wilkinson's catalyst in acetonitrile at 80 deg C to give the corresponding methylenecyclohex-2-enes usually in goog yield (62-83percent).Terminal substitution on either the alkene
