1195621-77-2

Basic information

• Product Name: 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde
• Synonyms: 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde
• CAS NO: 1195621-77-2
• Molecular Weight: 257.084
• Mol File: 1195621-77-2.mol

Chemical Properties

• CAS DataBase Reference: 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde(1195621-77-2)
• EPA Substance Registry System: 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde(1195621-77-2)

Safety Data

• Hazardous Substances Data: 1195621-77-2(Hazardous Substances Data)

Upstream product

• 39622-80-5 1,3-dimethyl 2-bromobenzene-1,3-dicarboxylate 
• 576-22-7 2-Bromo-m-xylene 
• 22433-91-6 2-bromoisophthalic acid 
• 59346-22-4 2,6-bis(hydroxymethyl)bromobenzene 
• 79839-49-9 2-bromoisophthalaldehyde 
• 107-21-1 ethylene glycol 

Downstream Products

• 1195621-85-2 C₁₀H₁₁BrO₃ 
• 1268335-77-8 N-phenyl-3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]borazole-7-yl)propanamide 
• 1268335-79-0 3-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-N-(4-methoxylphenyl)propanamide 
• 1268335-80-3 3-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-N-(4-((tert-butoxycarbonyl)aminomethyl)phenyl)propanamide 
• 1268335-81-4 7-{2'-[4''-(aminoethyl)phenylcarbamoyl]ethyl}-1,3-dihydro-1-hydroxy-2,1-benzoxaborole 
• 1195621-92-1 (E)-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-O-benzyl oxime 
• 1195621-86-3 2-(2-bromo-3-methoxymethoxymethyl-phenyl)-[1,3]dioxolane 
• 1268335-33-6 3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)propanoic acid 
• 1315513-33-7 3-(1,3-dioxolan-2-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde 

Relevant articles and documents

BICYCLIC HETEROCYCLYL COMPOUNDS AND USES THEREOF

The present disclosure is directed to modulators of SOS1 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS

This invention provides novel compounds of the following formula useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

An efficient synthesis for a new class antimalarial agent, 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

Efficient synthesis is essential for antimalarial therapeutics. A four-step route has been established for the synthesis of 7-(2-carboxyethyl)-1,3-dihydro- 1-hydroxy-2,1-benzoxaborole 1 that is a potent new class boron-containing antimalarial agent in pre

Convenient and versatile synthesis of formyl-substituted benzoxaboroles

Despite of the medicinal significance of benzoxaboroles, with the newly discovered clinical compound AN2690 as an example, the synthetic method for rapid diversification of this novel scaffold is lacking. To this end, a versatile and scalable synthesis of formyl-substituted benzoxaboroles is described here. A key step is the mono-oxidation of the two hydroxyls in compound 4 by taking advantage of the stable oxaborole ring in non-coordinating solvents, which was devised based on the study of the intramolecular coordination and exchange properties.