1195621-85-2

Basic information

• Product Name: C₁₀H₁₁BrO₃
• Synonyms: C₁₀H₁₁BrO₃
• CAS NO: 1195621-85-2
• Molecular Weight: 259.1
• Mol File: 1195621-85-2.mol

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₁BrO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₁BrO₃(1195621-85-2)
• EPA Substance Registry System: C₁₀H₁₁BrO₃(1195621-85-2)

Safety Data

• Hazardous Substances Data: 1195621-85-2(Hazardous Substances Data)

Upstream product

• 39622-80-5 1,3-dimethyl 2-bromobenzene-1,3-dicarboxylate 
• 79839-49-9 2-bromoisophthalaldehyde 
• 576-22-7 2-Bromo-m-xylene 
• 22433-91-6 2-bromoisophthalic acid 
• 59346-22-4 2,6-bis(hydroxymethyl)bromobenzene 
• 1195621-77-2 2-bromo-3-(1,3-dioxolan-2-yl)benzaldehyde 

Downstream Products

• 1195621-86-3 2-(2-bromo-3-methoxymethoxymethyl-phenyl)-[1,3]dioxolane 
• 1268335-77-8 N-phenyl-3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]borazole-7-yl)propanamide 
• 1268335-79-0 3-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-N-(4-methoxylphenyl)propanamide 
• 1268335-80-3 3-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-N-(4-((tert-butoxycarbonyl)aminomethyl)phenyl)propanamide 
• 1268335-81-4 7-{2'-[4''-(aminoethyl)phenylcarbamoyl]ethyl}-1,3-dihydro-1-hydroxy-2,1-benzoxaborole 
• 1195621-92-1 (E)-(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl)-O-benzyl oxime 
• 1268335-33-6 3-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-7-yl)propanoic acid 

Relevant articles and documents

BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS

This invention provides novel compounds of the following formula useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Convenient and versatile synthesis of formyl-substituted benzoxaboroles

Despite of the medicinal significance of benzoxaboroles, with the newly discovered clinical compound AN2690 as an example, the synthetic method for rapid diversification of this novel scaffold is lacking. To this end, a versatile and scalable synthesis of formyl-substituted benzoxaboroles is described here. A key step is the mono-oxidation of the two hydroxyls in compound 4 by taking advantage of the stable oxaborole ring in non-coordinating solvents, which was devised based on the study of the intramolecular coordination and exchange properties.