1195931-32-8

Basic information

• Product Name: 4-chloro-N-[3-(4-(cyanomethoxy)-phenylamino)-quinoxalin-2-yl]-benzene sulfonamide
• Synonyms: 4-chloro-N-[3-(4-(cyanomethoxy)-phenylamino)-quinoxalin-2-yl]-benzene sulfonamide
• CAS NO: 1195931-32-8
• Molecular Weight: 465.92
• Mol File: 1195931-32-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-N-[3-(4-(cyanomethoxy)-phenylamino)-quinoxalin-2-yl]-benzene sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N-[3-(4-(cyanomethoxy)-phenylamino)-quinoxalin-2-yl]-benzene sulfonamide(1195931-32-8)
• EPA Substance Registry System: 4-chloro-N-[3-(4-(cyanomethoxy)-phenylamino)-quinoxalin-2-yl]-benzene sulfonamide(1195931-32-8)

Safety Data

• Hazardous Substances Data: 1195931-32-8(Hazardous Substances Data)

Upstream product

• 98-64-6 4-Chlorobenzenesulfonamide 
• 2213-63-0 2,3-dichloroquinoxaline 
• 522628-95-1 4-chloro-N-(3-chloro-quinoxalin-2-yl)-benzenesulfonamide 
• 169286-84-4 (4-amino-phenoxy)-acetonitrile 

Relevant articles and documents

TARGETING AN HIV-1 NEF-HOST CELL KINASE COMPLEX

Drug candidates for inhibition of HIV-I replication can target Src family kinases (SFK), such as Hck, that interact with Nef protein of the virus. Compounds characterized by such inhibitory activity were identified via an assay for kinase activity of an SFK in a Nef:SFK complex. Illustrative of inhibitors identified using the kinase assay are various 2,3- diaminoquinaxolines and furo[2,3-d]pyrimidines. The inventive inhibitors were found to arrest HIV-I viral replication in vitro.