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2-(bromomethyl)-5-chloro-4-phenyloxazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1195985-50-2

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1195985-50-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1195985-50-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,5,9,8 and 5 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1195985-50:
(9*1)+(8*1)+(7*9)+(6*5)+(5*9)+(4*8)+(3*5)+(2*5)+(1*0)=212
212 % 10 = 2
So 1195985-50-2 is a valid CAS Registry Number.

1195985-50-2Relevant academic research and scientific papers

Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl) methanamines as potent and efficacious type II calcimimetics

Poon, Steve F.,St Jean Jr., David J.,Harrington, Paul E.,Henley III, Charles,Davis, James,Morony, Sean,Lott, Fred D.,Reagan, Jeff D.,Lu, Jenny Ying-Lin,Yang, Yuhua,Fotsch, Christopher

supporting information; experimental part, p. 6535 - 6538 (2010/04/03)

Our efforts to discover potent, orally bioavailable type II calcimimetic agents for the treatment of secondary hyperparathyroidism focused on the development of ring constrained analogues of the known calcimimetic R-568. The structure-activity relationships of various substituted heterocycles and their effects on the human calcium-sensing receptor are discussed. Pyrazole 15 was shown to be efficacious in a rat in vivo pharmacodynamic model.

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