119616-58-9Relevant academic research and scientific papers
Total Synthesis of 6-Methyl-5-androstene-3,11,17-trione 3-Ethylene Acetal, Building Block for 6α-Methylprednisolone
Daniewski, Andrzej Robert,Piotrowska, Emilia
, p. 571 - 576 (2007/10/02)
The total synthesis of 6-methyl-5-androstene-3,11,17-trione 3-ethylene acetal (25) in 13 steps is described.The coupling reaction of the potassium salt of tert-butyl α-propionylpropionate with the readily available sulfone 2, followed by catalytic hydroge
