119618-52-9

Upstream product

• 119588-70-4 (2R,3S)-2-Amino-3-hydroxy-3-[(2S,4S,5R)-4-methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propionic acid 
• 119588-68-0 (E)-3-[(2S,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-propenal 
• 108591-33-9 N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-4-methylbenzene sulfonamide 

Downstream Products

• 119588-79-3 (2S,4S,5R,4'S,5'S)-4-Methyl-2'-oxo-5-phenyl-3-(toluene-4-sulfonyl)-[2,5']bioxazolidinyl-3',4'-dicarboxylic acid 3'-tert-butyl ester 4'-methyl ester 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS OF FUNCTIONALIZED α-AMINO-β-HYDROXY ACIDS VIA CHIRAL NOREPHEDRINE-DERIVED OXAZOLIDINES

Both anti and syn enantiomerically pure functionalized α-amino-β-hydroxy acids and derivatives were synthesized starting from norephedrine-derived oxazolidine (1).The key-steps of the synthesis were the nucleophilic epoxidation of (1) and the nucleophilic