119588-70-4Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS OF 3,4-CIS-SUBSTITUTED β-LACTAMS VIA CHIRAL NOREPHEDRINE-DERIVED OXAZOLIDINES.
Cardani, S.,Gennari, C.,Scolastico, C.,Villa, R.
, p. 7397 - 7404 (2007/10/02)
A diastereo- and enantioselective approach to functionalized 3,4-cis-β-lactams 9 and 16 was developed based on the use of chiral norephedrine-derived oxazolidines.The key-steps in the synthesis of 9 (Scheme 1) are the potassium hypochlorite epoxidation of
ASYMMETRIC SYNTHESIS OF FUNCTIONALIZED α-AMINO-β-HYDROXY ACIDS VIA CHIRAL NOREPHEDRINE-DERIVED OXAZOLIDINES
Cardani, Silvia,Bernardi, Anna,Colombo, Lino,Gennari, Cesare,Scolastico, Carlo,Venturini, Isabella
, p. 5563 - 5572 (2007/10/02)
Both anti and syn enantiomerically pure functionalized α-amino-β-hydroxy acids and derivatives were synthesized starting from norephedrine-derived oxazolidine (1).The key-steps of the synthesis were the nucleophilic epoxidation of (1) and the nucleophilic
