1196449-89-4Relevant academic research and scientific papers
BIFUNCTIONAL MOLECULES WITH ANTIBODY-RECRUITING AND ENTRY INHIBITORY ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS
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, (2012/11/07)
The present invention is directed to new bifunctional compounds and methods for treating HIV infections. The bifunctional small molecules, generally referred to as ARM-H′ function through orthogonal pathways, by inhibiting the gp120-CD4 interaction, and b
An antibody-recruiting small molecule that targets HIV gp120
Parker, Christopher G.,Domaoal, Robert A.,Anderson, Karen S.,Spiegel, David A.
supporting information; experimental part, p. 16392 - 16394 (2010/02/16)
(Chemical Equation Presented) HIV/AIDS is a global pandemic for which new treatment strategies are desperately needed. We have designed a novel small molecule, designated as ARM-H, that has the potential to interfere with HIV survival through two mechanis
