1196658-71-5

Basic information

• Product Name: 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole
• Synonyms: 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole
• CAS NO: 1196658-71-5
• Molecular Weight: 472.455
• Mol File: 1196658-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole(1196658-71-5)
• EPA Substance Registry System: 1-(3,4,6-tri-O-acetyl-1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole(1196658-71-5)

Safety Data

• Hazardous Substances Data: 1196658-71-5(Hazardous Substances Data)

Upstream product

• 33143-80-5 3-(p-cyanophenoxy)-1-propyne 
• 1196658-68-0 3,4,6-tri-O-acetyl-1,5-anhydro-2-azido-2-deoxy-D-galactitol 

Downstream Products

• 1196658-77-1 1-(1,5-anhydro-2-deoxy-D-galactitol-2-yl)-4-(4-cyanophenoxy)methyl-1,2,3-triazole 

Relevant articles and documents

Design, synthesis and evaluation of monovalent ligands for the asialoglycoprotein receptor (ASGP-R)

A series of novel aryl-substituted triazolyl d-galactosamine derivatives was synthesized as ligands for the carbohydrate recognition domain of the major subunit H1 (H1-CRD) of the human asialoglycoprotein receptor (ASGP-R). The compounds were biologically evaluated with a newly developed competitive binding assay, surface plasmon resonance and by a competitive NMR binding experiment. With compound 1b, a new ligand with a twofold improved affinity to the best so far known d-GalNAc was identified. This small, drug-like ligand can be used as targeting device for drug delivery to hepatocytes.