1196664-99-9

Upstream product

• 1196664-98-8 C₂₁H₂₈BrN₂O₅P 
• 207516-23-2 tert-butyl (4S,5R,1'E)-4-(hydroxymethyl)-2,2-dimethyl-5-(pentadec-1'-enyl)-oxazolidine-3-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 123-78-4 (2S,3R,4E)-2-amino-4-octadecene-1,3-diol 
• 116467-63-1 N-tert-butyloxycarbonylsphingosine 
• 5367-32-8 5-methoxy-2-nitrotoluene 
• 861076-28-0 1-bromo-2-methoxy-4-methyl-5-nitrobenzene 
• 1196664-96-6 4-bromo-5-methoxy-2-nitrobenzaldehyde 
• 1196664-97-7 (4-bromo-5-methoxy-2-nitrophenyl)(phenyl)methanol 

Downstream Products

• 1196665-00-5 tert-butyl (4S,5R,1E)-4-((((4'-bromo-5'-methoxy-2'-nitrophenyl)(phenyl)methoxy)(methoxy)phosphoryloxy)methyl)-2,2-dimethyl-5-(pentadec-1-enyl)oxazolidine-3-carboxylate 
• 1196665-02-7 (4'-bromo-5'-hydroxy-2'-nitrophenyl)(phenyl)methyl-(2S,3R,4E)-3-hydroxy-2-palmitamidooctadec-4-enyl hydrogen phosphate 
• 1196665-01-6 (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-enyl-(4'-bromo-5'-hydroxy-2'-nitrophenyl)(phenyl)methyl hydrogen phosphate 
• 1300618-29-4 4-bromo-5-hydroxy-2-nitroso-benzophenone 

Relevant academic research and scientific papers

CAGED CERAMIDE-1-PHOSPHATE DERIVATIVES

The invention relates to novel caged ceramide 1-phosphate (C1P) and the method of using them for delivering C1P intracellularly in vitro and in vivo, for research and therapeutic purposes.

Caged ceramide 1-phosphate analogues: Synthesis and properties

(Chemical Equation Presented) Sphingolipid phosphate analogues bearing 7-(diethylamino)-coumarin (DECM) and 4-bromo-5-hydroxy-2-nitrobenzhydryl (BHNB) groups in a photolabile ester bond were synthesized. The ability of the "caged" ceramide 1-phosphate analogues to release the bioactive parent molecule upon irradiation at 400-500 nm was demonstrated by stimulation of macrophage cell proliferation. 2009 American Chemical Society.