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HSF1A, a member of the heat shock protein family, is a transcription factor that plays a pivotal role in cellular protection and repair mechanisms. It is activated in response to various stressors, such as heat, toxins, and environmental changes, and is instrumental in maintaining cellular homeostasis and safeguarding against cellular damage. HSF1A's involvement in the regulation of cellular stress responses positions it as a significant factor in the development of therapeutic strategies for diseases related to protein misfolding and cellular stress.

1196723-93-9

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1196723-93-9 Usage

Uses

Used in Pharmaceutical Industry:
HSF1A is used as a therapeutic target for the development of treatments aimed at diseases associated with protein misfolding and cellular stress. Its role in activating the expression of other heat shock proteins and its involvement in cellular stress responses make it a promising candidate for interventions in conditions such as neurodegenerative diseases, where protein misfolding and aggregation are common pathological features.
Used in Biotechnology Industry:
HSF1A is utilized as a tool in biotechnological applications for enhancing cellular resilience and stress tolerance in engineered organisms or cell lines. By modulating HSF1A activity, researchers can improve the performance and stability of bioprocesses, particularly in the production of therapeutic proteins or other bioproducts under stressful conditions.
Used in Research Applications:
HSF1A serves as a valuable research subject for understanding the molecular mechanisms underlying cellular stress responses and the role of heat shock proteins in maintaining cellular homeostasis. Studying HSF1A can provide insights into the development of novel therapeutic approaches and the identification of biomarkers for stress-related diseases.
Used in Drug Discovery:
HSF1A is employed as a target for drug discovery efforts focused on identifying small molecules or biologics that can modulate its activity. These compounds may have potential as therapeutic agents for the treatment of diseases characterized by protein misfolding and cellular stress, offering new avenues for intervention and management of such conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1196723-93-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,6,7,2 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1196723-93:
(9*1)+(8*1)+(7*9)+(6*6)+(5*7)+(4*2)+(3*3)+(2*9)+(1*3)=189
189 % 10 = 9
So 1196723-93-9 is a valid CAS Registry Number.

1196723-93-9Downstream Products

1196723-93-9Relevant academic research and scientific papers

COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF

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Page/Page column 21-22, (2011/05/16)

The present invention relates to HSF activating compounds, methods for their discovery, and their research and therapeutic uses, as well as pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, mixtures (including both R

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