1197002-91-7Relevant academic research and scientific papers
Recognition of dicarboxylic acids by a bis pyrimidine amine linked xylene spacer: A unique gauche dimeric complex of host and adipic acid detected by X-ray
Goswami, Shyamaprosad,Hazra, Anita,Fun, Hoong-Kun
scheme or table, p. 461 - 466 (2011/12/03)
A pyrimidine based receptor (pyrimidine amine linked xylene spacer) has been synthesized for recognition of dicarboxylic acids. Binding studies have been performed by UV-vis method by varying the chain length of dicarboxylic acids. The downfield chemical shift of amine protons of receptor in presence of adipic acid or glutaric acid and the 1:1 dimeric crystal structure of the receptor and adipic acid reveal the strong binding interaction.
One-pot two-step solvent-free rapid and clean synthesis of 2-(substituted amino)pyrimidines by microwave irradiation
Goswami, Shyamaprosad,Hazra, Anita,Jana, Subrata
experimental part, p. 1175 - 1181 (2009/12/25)
abs A series of diversely 2-(substituted amino)pyrimidines (along with ring substitution) has been synthesized under solvent- and catalyst-free microwave conditions from substituted guanidines and β-diketones. The substituted guanidines are synthesized from (S)-methylisothiourea sulfate and different amines (various alkyl, aryl, or heterocyclic and also chiral amines) under microwave irradiation. These two-step reactions are performed in one-pot without isolating any intermediate. This protocol has been successfully applied for the synthesis of bisaminopyrimidines and 2-substituted aminopyrimidines containing chiral moiety where chirality remains undisturbed.
