1197006-60-2

Basic information

• Product Name: 1-phenyl(tetrahydro-2H-pyran-4-yl)methylamine
• Synonyms: 1-phenyl(tetrahydro-2H-pyran-4-yl)methylamine
• CAS NO: 1197006-60-2
• Molecular Weight: 191.273
• Mol File: 1197006-60-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-phenyl(tetrahydro-2H-pyran-4-yl)methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl(tetrahydro-2H-pyran-4-yl)methylamine(1197006-60-2)
• EPA Substance Registry System: 1-phenyl(tetrahydro-2H-pyran-4-yl)methylamine(1197006-60-2)

Safety Data

• Hazardous Substances Data: 1197006-60-2(Hazardous Substances Data)

Usage

Molecular structure

Consists of a phenyl group attached to a tetrahydro-2H-pyran-4-ylmethylamine group.

Type of compound

Tertiary amine.

Usage

Commonly used in organic synthesis as a building block for the production of various pharmaceuticals and other organic compounds.

Unique properties

Presence of the tetrahydro-2H-pyran-4-yl group gives it unique properties.

Applications

Valuable intermediate in the synthesis of various drugs, including antidepressants and antiviral medications.

Potential

May have potential applications in medicinal chemistry and drug design due to its structural features and pharmacological properties.

Upstream product

• 40191-32-0 tetrahydro-2H-pyran-4-carbonylchloride 
• 639468-72-7 phenyl(tetrahydro-2H-pyran-4-yl)methanone 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 

Downstream Products

• 1430473-15-6 3-iodo-N-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-1H-indazole-5-carboxamide 

Relevant articles and documents

Aromatic-ring-containing compound, preparation method thereof, pharmaceutical composition and application thereof

The invention discloses an aromatic-ring-containing compound, a preparation method thereof, a pharmaceutical composition and application. The present invention provides the aromatic-ring-containing compound represented by a formula 1, a pharmaceutically acceptable salt thereof, a stereoisomer thereof, a tautomer thereof or a solvate thereof, and the aromatic-ring-containing compound can be effectively bounded to bromodomains of BRD4, BRD3, BRD2, and BRDT in BET family to regulate transcription of downstream gene c-myc and related target genes of the c-myc so as to regulate downstream signalingpathways to play specific roles including treatment of diseases such as inflammatory diseases, cancer, and AIDS. Some of the compounds have high activity, and have good cell activity and metabolic stability, so that the compounds can be an effective drug for treating tumors.

BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS

The present invention relates to Bicyclic Heterocycle Derivatives of formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR1 19 in a patient.