119702-41-9Relevant academic research and scientific papers
SYNTHESIS OF 1,2-GLYCOL MONOETHERS UTILIZING DECARBONYLATION OF α-ALKOXYACID CHLORIDES MEDIATED BY SAMARIUM DIIODIDE
Sasaki, Mitsuru,Collin, Jacqueline,Kagan, Henri B.
, p. 4847 - 4850 (2007/10/02)
A new synthesis of 1,2-glycol monoethers has been achived by utilizing decarbonylation of α-alkoxyacid chlorides mediated by samarium diiodide in the presence of ketones.This one-pot reaction works within a few minutes at room temperature.The structure of α-alkoxyacid chlorides (R2,R3)C(OR1)COCl2 tolerates various substitution patterns (R2=R3=H; R2=H; R3=Me or R2=R3=Me).
