1197026-50-8

Basic information

• Product Name: C₁₄H₁₈N₂O₄
• Synonyms: C₁₄H₁₈N₂O₄
• CAS NO: 1197026-50-8
• Molecular Weight: 278.308
• Mol File: 1197026-50-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₈N₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₈N₂O₄(1197026-50-8)
• EPA Substance Registry System: C₁₄H₁₈N₂O₄(1197026-50-8)

Safety Data

• Hazardous Substances Data: 1197026-50-8(Hazardous Substances Data)

Upstream product

• 40734-77-8 N-[(phenyl)(tosyl)methyl]urea 
• 141-97-9 ethyl acetoacetate 
• 100-52-7 benzaldehyde 
• 57-13-6 urea 

Relevant articles and documents

Towards Enzyme-like, Sustainable Catalysis: Switchable, Highly Efficient Asymmetric Synthesis of Enantiopure Biginelli Dihydropyrimidinones or Hexahydropyrimidinones

Organocatalysts displaying a network of cooperative hydrogen bonds (NCHB) have been employed in an enzyme-like manner for a direct, switchable synthesis of enantiopure hexahydropyrimidinones (HHPMs) or dihydropyrimidinones (DHPMs), which starts at a common, easily accessible α-ureidosulfone stage. The NCHB organocatalyst exploits all its potential as a pure hydrogen-bond biomimetic catalyst even in the presence of organic bases. This one-pot, diastereo- and enantioselective synthetic procedure has been proven to be robust, scalable, highly efficient, and environmentally benign. A straightforward and truly practical entry to enantiopure HHPMs is reported for the first time.