119730-10-8

Upstream product

• 56-04-2 2-mercapto-6-methylpyrimidin-4(3H)-one 
• 937-20-2 p-chlorophenacyl chloride 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 56-04-2 6-methyl-2-thiouracil 
• 56-04-2 6-methyl-2-thiouracil 

Downstream Products

• 119730-51-7 2-(4-chlorobenzoylmethylene)-6-methyl-2,3-dihydropyrimidin-4(1H)-one 
• 23429-91-6 3-(4-chlorophenyl)-7-methyl-5H-thiazolo<3,2-a>pyrimidin-5-one 
• 1174924-48-1 C₁₃H₁₁ClN₂O₂ 
• 1333506-23-2 2-[2-(4-chlorophenyl)-2-hydroxyvinyl]-6-methylpyrimidin-4-ol 

Relevant academic research and scientific papers

Synthesis of some new thiazolo[3,2-A]pyrimidine derivatives and screening of their in vitro antibacterial and antitubercular activities

The novel 5H-thiazolo[3,2-A]pyrimidin-5-ones were synthesized by thiophene ring closure. The first step is the synthesis of S-alkylated derivatives by the reaction of 6-substituted-2-thiouracils with the appropriate substituted phenacyl halides. Upon trea

The Eschenmoser coupling reaction under continuous-flow conditions

The Eschenmoser coupling is a useful carbon-carbon bond forming reaction which has been used in various different synthesis strategies. The reaction proceeds smoothly if S-alkylated ternary thioamides or thiolactames are used. In the case of S-alkylated s

Antimicrobial, antitumor and 5α-reductase inhibitor activities of some hydrazonoyl substituted pyrimidinones

A series of 2-[N-aryl-2-oxo-2-(4-chlorophenyl)ethanehydrazonoyl]-6-methyl- 4(3H)-pyrimidinones 5 were prepared by coupling the diazonium salt of aniline derivatives with 2-(4-chlorobenzoylmethylene)-6-methyl-4(3H)-pyrimidinone 4 in sodium hydroxide soluti

The Chemistry of Pyrimidinethiols. II. The Preparation and Reaction of Some 2-Arenecarbonylmethylthiopyrimidines

A number of 2-arenecarbonylmethylthiopyrimidin-4(1H)-ones has been synthesized.Those having H, Me or Pr as a 6-substituent undergo ready sulfur extrusion on heating in diphenyl ether to give 2-(arenecarbonylmethylene)-2,3-dihydropyrimidin-4(1H)-ones, but