119736-43-5

Upstream product

• 95-48-7 ortho-cresol 
• 100-07-2 4-methoxy-benzoyl chloride 
• 2989-17-5 methyl 2-methylphenoxy acetate 
• 115057-32-4 methyl 4-(4'-methoxybenzoyl)-2-methylphenoxyacetate 

Downstream Products

• 145089-11-8 <4-<<<9H-fluoren-9-yl-methoxycarbonyl>amino>(4-methoxyphenyl)methyl>-2-methylphenoxy>acetic acid 
• 115057-35-7 <4-<(4-methoxyphenyl)methyl>-2-methylphenoxy>acetic acid 

Relevant academic research and scientific papers

SOLID PHASE SYNTHESIS OF A SOMATOSTATIN AMIDE ANALOGUE USING ACID LABILE t-BUMEOC PROTECTION AND AN ACID LABILE ANCHOR GROUP

The solid phase synthesis of an amidated somatostatin analogue based on the principle of differentiated acidolysis is described.The acid labile and smoothly cleavable t-Bumeoc moiety (1percent TFA/DCM) is used for temporary Nα-protection of D- and L-amino acids and amino>(4-methoxyphenyl)methyl>-2-methylphenoxy>acetic acid, attached to an aminomethylated polystyrene resin is used as acid sensitive linker of the solid carrier which releases the peptide in its amide form by treatment with TFA.Its preparation is described in detail.

Synthesis of peptide amides by means of a solid phase method using acid-labile anchoring groups

The invention relates to new compounds of the formula STR1 in which R1 denotes (C1 -C8)-alkyl or optionally substituted (C6 -C14)-aryl, R2 denotes hydrogen or an amino acid residue which is