119785-58-9Relevant academic research and scientific papers
Practical one-pot stereospecific preparation of vicinal and 1,3-diols
Bohman, Bjorn,Flematti, Gavin R.,Unelius, C. Rikard
supporting information, p. 75 - 77 (2016/12/23)
A facile one-pot synthesis providing vicinal diols and 1,3-diols in >95% stereoisomeric purity from commercially available enantiopure hydroxy esters has been developed. The esters were reduced with DIBALH and alkylated in situ with 4-pentenylmagnesium br
Synthesis of taurospongin A
Wu, Boshen,Mallinger, Aurelie,Robertson, Jeremy
supporting information; experimental part, p. 2818 - 2821 (2010/09/03)
(Figure presented) Two new routes to the C(1-10) carboxylic acid core of taurospongin A are presented. In the first route, overall asymmetric hydration of a C(2)-C(3) alkene is achieved by Sharpless AD and selective deoxygenation at C(2); in the second route, the C(3) stereogenic center is set by Tietze asymmetric allylation. A short synthesis of the C(1′-25′) fatty acid combines with the product from the first route to complete the total synthesis of taurospongin A.
