1197995-88-2Relevant academic research and scientific papers
Synthesis of All diastereomers of the piperidine - alkaloid substructure of cyclopamine
Heretsch, Philipp,Rabe, Sebastian,Giannis, Athanasslos
, p. 5410 - 5412 (2009)
"Chemical Equation Presented" All four diastereomers of the trisubstituted piperidine-alkaloids of the veratramine and jervine type were synthesized with complete stereocontrol starting from enantiopure citronellic acids. The flexible, high-yielding, and scalable route described here will facilitate convergent syntheses and give access to analogues of cyclopamine and other biologically active and diverse steroid alkaloids.
