1198-83-0 Usage
General Description
2-methylsulfanyl-7H-purin-6-amine is a chemical compound that belongs to the class of purine derivatives. It is a derivative of adenine, which is a fundamental component of nucleic acids such as DNA and RNA. 2-methylsulfanyl-7H-purin-6-amine contains a purine ring with a methylsulfanyl group attached at the 2-position and an amine group at the 6-position. It has potential biological activities and has been studied for its potential pharmacological applications, particularly in the field of medicinal chemistry and drug development. The compound's structure and properties make it an interesting target for further research in the fields of biochemistry and pharmaceutical sciences.
Check Digit Verification of cas no
The CAS Registry Mumber 1198-83-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,9 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1198-83:
(6*1)+(5*1)+(4*9)+(3*8)+(2*8)+(1*3)=90
90 % 10 = 0
So 1198-83-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N5S/c1-12-6-10-4(7)3-5(11-6)9-2-8-3/h2-3H,1H3,(H2,7,8,9,10,11)
1198-83-0Relevant articles and documents
BF3·SMe2 for Thiomethylation, Nitro Reduction and Tandem Reduction/SMe Insertion of Nitrogen Heterocycles
S?derstr?m, Marcus,Zamaratski, Edouard,Odell, Luke R.
, p. 5402 - 5408 (2019/06/27)
Herein, a general, solvent-free and straightforward thiomethylation of electron deficient heterocycles using BF3·SMe2 as a dual thiomethyl source and Lewis acidic activator is presented. A range of heterocycles including pyrimidine, pyrazine, pyridazine, thiazole and purine derivatives were successfully substituted using this method. An unexpected reductive property of BF3·SMe2 towards nitropyridines was also discovered including an intriguing tandem reduction/SMe insertion process in certain substrates. Notable features of the present work include its convenience and use of a non-malodorous reagent while the discovery of novel chemical transformations using BF3·SMe2 provides fundamental new insights into the reactivity of this commonly employed reagent.
