1198107-08-2Relevant academic research and scientific papers
Asymmetric catalysis of the carbonyl-amine condensation: Kinetic resolution of primary amines
Das, Sayantani,Majumdar, Nilanjana,De, Chandra Kanta,Kundu, Dipti Sankar,Dohring, Arno,Garczynski, Anika,List, Benjamin
supporting information, p. 1357 - 1359 (2017/02/10)
A Br?nsted acid catalyzed kinetic resolution of primary amines is described that is based on the condensation between an amine and a carbonyl compound. 1,3-Diketones react with racemic α-branched amines to furnish the corresponding enantioenriched enaminone and recovered starting material. Good to excellent enantioselectivity was observed with both aromatic and aliphatic primary amines. This process represents the first small-molecule catalyzed kinetic resolution of aliphatic amines.
Organocatalytic asymmetric biomimetic transamination of aromatic ketone to optically active amine
Xie, Ying,Pan, Hongjie,Xiao, Xiao,Li, Songlei,Shi, Yian
supporting information, p. 8960 - 8962,3 (2012/12/12)
An asymmetric biomimetic transamination of aromatic ketones to optically active amines with o-HOPhCH2NH2 as amine source catalyzed by hydroquinine-derived chiral base is described. Up to 85% ee was obtained.
Organocatalytic asymmetric biomimetic transamination of aromatic ketone to optically active amine
Xie, Ying,Pan, Hongjie,Xiao, Xiao,Li, Songlei,Shi, Yian
supporting information, p. 8960 - 8962 (2013/01/15)
An asymmetric biomimetic transamination of aromatic ketones to optically active amines with o-HOPhCH2NH2 as amine source catalyzed by hydroquinine-derived chiral base is described. Up to 85% ee was obtained.
