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Dexloxiglumide is a selective and competitive antagonist of cholecystokinin (CCK) receptors, particularly the CCKA receptors. It is an investigational drug with potential applications in the treatment of gastrointestinal disorders.
Used in Pharmaceutical Industry:
Dexloxiglumide is used as a therapeutic agent for the treatment of gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome. It works by blocking the action of CCK, reducing the release of digestive enzymes and bile from the pancreas and gallbladder, which may help alleviate symptoms of these conditions.
Used in Gastrointestinal Research:
Dexloxiglumide is used as a research tool to study the role of CCK receptors in gastrointestinal motility and visceral hypersensitivity. Its ability to modulate these processes provides insights into the underlying mechanisms of functional gastrointestinal disorders and may contribute to the development of novel treatment strategies.

119817-90-2

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119817-90-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 119817-90-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,9,8,1 and 7 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 119817-90:
(8*1)+(7*1)+(6*9)+(5*8)+(4*1)+(3*7)+(2*9)+(1*0)=152
152 % 10 = 2
So 119817-90-2 is a valid CAS Registry Number.
InChI:InChI=1/C21H30Cl2N2O5/c1-3-4-5-11-25(12-6-13-30-2)21(29)18(9-10-19(26)27)24-20(28)15-7-8-16(22)17(23)14-15/h7-8,14,18H,3-6,9-13H2,1-2H3,(H,24,28)(H,26,27)/t18-/m1/s1

119817-90-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (4R)-4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid

1.2 Other means of identification

Product number -
Other names CR-2017

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:119817-90-2 SDS

119817-90-2Downstream Products

119817-90-2Relevant academic research and scientific papers

Preparation method of dexloxiglumide

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Paragraph 0039; 0046; 0047, (2019/01/06)

The invention discloses a preparation method of dexloxiglumide. The preparation method comprises the following steps: carrying out an acylation reaction on N-boc-D-glutamic acid-5-benzyl ester with N-(3-methoxypropyl)-amylamine by a mixed anhydride method, then removing boc groups to obtain the following compound, then carrying out a reaction on the obtained compound with 3,4-dichlorobenzoyl chloride to generate the following compound, and finally removing benzyl groups to obtain dexloxiglumide. Compared with the prior art, the method provided by the invention is simpler in operation and is more efficient.

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