1198185-68-0

Basic information

• Product Name: Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate
• Synonyms: Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate
• CAS NO: 1198185-68-0
• Molecular Weight: 734.914
• Mol File: 1198185-68-0.mol

Chemical Properties

• CAS DataBase Reference: Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate(1198185-68-0)
• EPA Substance Registry System: Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate(1198185-68-0)

Safety Data

• Hazardous Substances Data: 1198185-68-0(Hazardous Substances Data)

Upstream product

• 1198185-28-2 (9S,12R)-12-amino-9-isopropyl-2,7-dioxa-1O-aza-bicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-11-one 
• 732211-08-4 Benzyl (R)-2-amino-3-(2-benzyloxycarbonylaminoethylsulfanyl)propionate 
• 530-62-1 1,1'-carbonyldiimidazole 
• 1198185-26-0 9H-fluoren-9-ylmethyl [(R)-1-[(S)-(1-allyloxymethyl-2-methylpropylcarbamoyl)]-2-(4-allyloxyphenyl)ethyl]carbamate 
• 1198185-64-6 Benzyl (R)-3-(2-benzyloxycarbonylaminoethylsulfanyl)-2-tert-butoxycarbonylaminopropionate 
• 85003-76-5 N-t-Butoxycarbonyl-S-(2-carbobenzyloxyaminoethyl)-L-cysteine 
• 1198185-27-1 9H-fluoren-9-ylmethyl ((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,4,14⁽¹⁸⁾,15-tetraen-12-yl)carbamate 
• 204269-35-2 (R)-3-(4-allyloxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid 
• 500708-37-2 (S)-1-(allyloxy)-3-methylbutan-2-amine 
• 154333-29-6 (S)-3-methyl-2-{[1-phenylmethylidene]amino}butan-1-ol 
• 100-51-6 benzyl alcohol 
• 2026-48-4 (S)-valinol 

Downstream Products

• 1198185-70-4 benzyl (R)-3-(2-benzyloxycarbonylaminoethanesulfonyl)-2-[3-((9S,12R)-9-isopropyl-11-oxo-2,7-dioxa-10-azabicyclo[12.2.2]octadeca-1⁽¹⁷⁾,14⁽¹⁸⁾,15-trien-12-yl)ureido]propionate 

Relevant articles and documents

MACROCYCLIC UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa

The invention relates to compounds of the formula (I) which are inhibitors of activated thrombin-activable fibrinolysis inhibitor. The compounds of the formula I are suitable for producing medicaments for prophylaxis, secondary prevention and treatment of one or more disorders associated with thromboses, embolisms, hypercoagulability or fibrotic changes.