119827-59-7Relevant articles and documents
Analogues of uridine 5'-diphosphate glucose and guanosine 5'-diphosphate mannose
Broxterman, H. J. G.,Kooreman, P. A.,Elst, H. van den,Roelen, H. C. P. F.,Marel, G. A. van der,Boom, J. H. van
, p. 583 - 590 (2007/10/02)
One-pot coupling of 2',3'-di-O-benzoyl-uridine and 4,5,6,8-tetra-O-acetyl-3,7-anhydro-2-deoxy-D-glycero-D-ido-octitol with appropriate bifunctional phosphoro-, phosphono- and thiophosphonylation reagents gave, after removal of the base-labile protecting groups, analogues of UDP-Glc containg charged phosphate, neutral alkyl- and arylphosphonate and phosphonothioate linkages.In an analogous manner, GDP-Man analogues, in which guanosine and octitol units are similarly linked via phosphate, alkyl phosphate or phosphotriester bonds, were prepared.