1198276-03-7

Basic information

• Product Name: (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one
• Synonyms: (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one
• CAS NO: 1198276-03-7
• Molecular Weight: 524.576
• Mol File: 1198276-03-7.mol

Chemical Properties

• CAS DataBase Reference: (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one(1198276-03-7)
• EPA Substance Registry System: (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one(1198276-03-7)

Safety Data

• Hazardous Substances Data: 1198276-03-7(Hazardous Substances Data)

Upstream product

• 19278-81-0 4-hydroxy-1-benzofuran-3(2H)-one 
• 1198278-03-3 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 

Relevant articles and documents

3-SUBSTITUTED-1H-INDOLE, 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES

The invention relates to 3-substituted-1H-indole, 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula (I): or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.

3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES

The invention relates to 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.