1198278-03-3

Basic information

• Product Name: 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
• Synonyms: 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde
• CAS NO: 1198278-03-3
• Molecular Weight: 392.458
• Mol File: 1198278-03-3.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde(1198278-03-3)
• EPA Substance Registry System: 4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde(1198278-03-3)

Safety Data

• Hazardous Substances Data: 1198278-03-3(Hazardous Substances Data)

Upstream product

• 1198277-84-7 4-bromo-1-methyl-1-H-pyrrolo[2,3-b]pyridine-3-carbaldehyde 
• 913943-06-3 (4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)boronic acid 

Downstream Products

• 1198276-03-7 (2Z)-4-hydroxy-2-{[4-(4-{[4-(2-hydroxyethyl)piperazin-1-yl]carbonyl}phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one 

Relevant articles and documents

Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

We discovered 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Since phenolic OH groups pose metabolic liability, one of th