1198362-07-0Relevant articles and documents
Enantioselective Michael addition of aldehydes to nitroolefins catalyzed by pyrrolidine-HOBt
Kumar, Togapur Pavan,Sattar, Mohammad Abdul,Prasad, Sthanikam Siva,Haribabu, Kothapalli,Reddy, Cirandur Suresh
, p. 401 - 409 (2017)
The oxytriazole catalyst “pyrrolidine-HOBt” developed for asymmetric Michael addition of cyclohexanone to nitroolefins is now evaluated for the asymmetric Michael addition of aldehydes to nitroolefins under similar reaction conditions. The results of this
Pyrrolidine-oxyimide catalyzed asymmetric Michael addition of α,α-disubstituted aldehydes to nitroolefins
Kumar, Togapur Pavan
, p. 907 - 911 (2015/09/01)
Abstract Organocatalytic enantioselective Michael addition of α,α-disubstituted aldehydes onto nitroolefins using pyrrolidine-oxyimide catalyst was reported. The reaction works effectively under neat conditions with 15 mol % of catalyst and 10 mol % of p-
Highly efficient asymmetric organocatalytic Michael addition of α,α-disubstituted aldehydes to nitroolefins under solvent-free conditions
He, Junpeng,Chen, Qiankun,Ni, Bukuo
supporting information, p. 3030 - 3032 (2014/05/20)
A chiral pyrrolide-based diamine in combination with benzoic acid has been found to be an effective organocatalyst for Michael addition of α,α-disubstituted aldehydes with nitroolefins. The reaction provided the desired Michael products possessing all-car
Enantioselective Michael addition of α,α-disubstituted aldehydes to nitroolefins catalyzed by a pyrrolidine-pyrazole
Kumar, Togapur Pavan,Haribabu, Kothapalli
, p. 1129 - 1132 (2014/09/17)
An efficient protocol for the asymmetric catalytic Michael additions of α,α-disubstituted aldehydes to nitroolefins with a pyrrolidine-pyrazole is described. The desired products γ-nitrocarbonyl compounds possessing an all-carbon quaternary center, were o
Calixarene-based highly efficient primary amine-thiourea organocatalysts for asymmetric Michael addition of aldehydes to nitrostyrenes
Durmaz, Mustafa,Sirit, Abdulkadir
, p. 292 - 301 (2013/06/04)
The synthesis of calix[4]arene-based chiral bifunctional primary amine-thiourea catalysts has been described from p-tert-butylcalix[4]arene for the first time. The calix[4]arene-based catalysts were successfully applied to promote Michael addition of alde
ORGANOCATALYST
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Page/Page column 10-11, (2011/04/14)
The present invention provides an organocatalyst of formula (I), wherein R1 is —H, —OH, —O—Si(R4)(R5)(R6) or C1-6alkoxy, in which R4, R5 and R6 are identical or differ
Pyrrolidinyl-camphor derivatives as a new class of organocatalyst for direct asymmetric Michael addition of aldehydes and ketones to β-nitroalkenes
Ting, Ying-Fang,Chang, Chihliang,Reddy, Raju Jannapu,Magar, Dhananjay R.,Chen, Kwunmin
supporting information; experimental part, p. 7030 - 7038 (2010/08/03)
Practical and convenient synthetic routes have been developed for the synthesis of a new class of pyrrolidinyl-camphor derivatives (7a-h). These novel compounds were screened as catalysts for the direct Michael addition of symmetrical αα-disubstituted ald
Pyrrolidine-camphor derivative as an organocatalyst for asymmetic michael additions of α,α-disubstituted aldehydes to β-nitroalkenes: Construction of quaternary carbon-bearing aldehydes under solvent-free conditions
Chang, Chihliang,Li, Ssu-Hsien,Reddy, Raju Jannapu,Chen, Kwunmin
experimental part, p. 1273 - 1278 (2009/12/22)
A novel pyrrolidine-camphor organocatalyst 3 was designed, synthesized and proven to be an efficient catalyst for the asymmetric Michael reaction. Treatment of α,α-disubstituted aldehydes with β-nitroalkenes in the presence of 20 mol% organocatalyst 3 and
