119844-66-5

Basic information

• Product Name: (5S)-5-methylmorpholin-3-one
• Synonyms: (5S)-5-methylmorpholin-3-one;(S)-5-MethylMorpholin-3-one;(5S)-5-Methyl-3-Morpholinone;(S)-5-Methyl-3-morpholinone;(S)-5-Methyl-3-morpholinone,99%e.e.
• CAS NO: 119844-66-5
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115
• Mol File: 119844-66-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 290.9°C at 760 mmHg
• Flash Point: 129.8°C
• Appearance: /
• Density: 1.046g/cm³
• Vapor Pressure: 0.00201mmHg at 25°C
• Refractive Index: 1.426
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (5S)-5-methylmorpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-methylmorpholin-3-one(119844-66-5)
• EPA Substance Registry System: (5S)-5-methylmorpholin-3-one(119844-66-5)

Safety Data

• Hazardous Substances Data: 119844-66-5(Hazardous Substances Data)

Usage

General Description

(5S)-5-methylmorpholin-3-one, also known as N-methylmorpholin-3-one or N-methyl-5-morpholinone, is a chemical compound with the molecular formula C5H9NO2. It is a cyclic amide with a morpholine ring and a methyl group attached to the nitrogen atom. (5S)-5-methylmorpholin-3-one is commonly used as a solvent and a reagent in organic synthesis. It is also used in the production of pharmaceuticals, dyes, and polymers. Its unique chemical structure and properties make it a versatile and valuable compound in various industrial and research applications.

InChI:InChI=1/C5H9NO2/c1-4-2-8-3-5(7)6-4/h4H,2-3H2,1H3,(H,6,7)/t4-/m0/s1

Upstream product

• 2749-11-3 (S)-Alaninol 
• 79-04-9 chloroacetyl chloride 
• 542-58-5 2-chloro-1-acetoxyethane 
• 94193-79-0 2-chloro-N-((S)-2-hydroxy-1-methylethyl)acetamide 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 1542268-18-7 4-(4-(2-aminothiazol-5-yl)-6-((S)-3-methylmorpholino)-1,3,5-triazin-2-yloxy)-3-fluoro-N,N-dimethylbenzamide hydrochloride 
• 1542268-21-2 C₂₅H₃₀FN₇O₅S 
• 1542268-20-1 C₁₇H₁₉ClFN₅O₃ 
• 1542268-12-1 (S)-4-((4-(6-aminopyridin-3-yl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)oxy)-3-fluoro-N,N-dimethylbenzamide hydrochloride 
• 1542267-11-7 (S)-4-((4-(6-aminopyridin-3-yl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)oxy)-3-fluoro-N,N-dimethylbenzamide 
• 1542268-17-6 C₂₄H₂₆FN₇O₄ 
• 1542268-08-5 (S)-4-((4-(6-aminopyridin-3-yl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)oxy)-N,N-dimethylbenzamide hydrochloride 
• 1542268-11-0 C₃₂H₄₁N₇O₇ 
• 1542268-10-9 C₁₇H₂₀ClN₅O₃ 
• 1542268-40-5 (S)-4-((4-(6-chloropyridin-3-yl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)oxy)-3-fluoro-N,N-dimethylbenzamide 
• 1542268-00-7 C₂₀H₂₃N₇O₃S*CH₄O₃S 
• 1542268-04-1 (S)-4-((4-(2-aminothiazol-5-yl)-6-(3-methylmorpholino)-1,3,5-triazin-2-yl)oxy)-N,N-dimethylbenzamide hydrochloride 
• 1542268-03-0 C₂₅H₃₁N₇O₅S 
• 350595-57-2 (S)-3-methylmorpholine 

Relevant articles and documents

Preparation method of (S)-(4-bromine-2-methylbenzene) (3-N-methylmorpholine) ketone

The invention discloses a preparation method of (S)-(4-bromine-2-methylbenzene) (3-N-methylmorpholine) ketone, and belongs to the technical field of organic synthesis. The invention is characterized in that the preparation method of the (S)-(4-bromine-2-m

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

PYRAZOLE DERIVATIVE

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.