1198592-17-4

Upstream product

• 1198592-01-6 1-(1,1-dimethylethyl) 6-methyl 3-phenyl-1H-indole-1,6-dicarboxylate 
• 860457-92-7 methyl 3-bromo-1H-indazole-6-carboxylate 
• 479552-81-3 3-bromoindole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester 
• 50820-65-0 indole-6-carboxylic acid methyl ester 
• 5394-18-3 2-(4-bromobutyl)isoindoline-1,3-dione 
• 1304126-83-7 methyl 1-(4-(1,3-dioxoisoindolin-2-yl)butyl)-1H-indole-6-carboxylate 
• 71-43-2 benzene 
• 1038997-75-9 3-phenylindole-6-carboxylic acid methyl ester 

Downstream Products

• 1198592-18-5 methyl 1-(4-aminobutyl)-3-phenyl-1H-indole-6-carboxylate 
• 1198592-58-3 methyl 3-phenyl-1-[4-(propylamino)butyl]-1H-indole-6-carboxylate 
• 1198592-19-6 methyl 1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylate 
• 1198591-51-3 1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylic acid 
• 1198593-02-0 methyl 2-bromo-1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylate 
• 1198593-06-4 methyl 2-formyl-1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylate 
• 1198593-03-1 methyl 2-ethenyl-1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylate 
• 1198593-07-5 methyl 2-[(methylamino)methyl]-1-[4-({[4-(1-methylethyl)phenyl]carbonyl}amino)butyl]-3-phenyl-1H-indole-6-carboxylate 
• 1198593-09-7 C₃₃H₃₉N₃O₃ 

Relevant academic research and scientific papers

Increasing synthetic efficiency via direct C-H functionalization: Formal synthesis of an inhibitor of botulinum neurotoxin

A new and efficient scheme for the synthesis of one of the best known inhibitors of botulinum neurotoxin serotype A (BoNTA) is reported herein. The synthetic route involves two palladium-catalyzed C-H functionalization reactions, formally activating three C-H bonds. The Royal Society of Chemistry 2011.

CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS

There is provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof wherein one of R1 and R2 is H and the other is COOH. The compounds are useful as PPAR modulators.